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Image (Illustration) Année : 2017

Weinreb β-Ketoamides in Enantioselective Organocatalysis: A Balance between Reactivity and Selectivity

Résumé

β-Dicarbonyl compounds have established themselves as substrates of choice in enantioselective organocatalysis because of their easy activation. Among them, β-diketones, β-diesters, and β-ketoesters lead the dance and there has been only limited work with other β-dicarbonyl compounds as pronucleophiles. In this Synpacts article, we wish to discuss our recent contributions to the introduction of Weinreb β-ketoamides in organocatalyzed transformations, where they can provide an interesting balance between reactivity and selectivity, with also interesting potentialities in terms of postfunctionalization.

Dates et versions

medihal-01723131 , version 1 (05-03-2018)

Licence

Domaine public

Identifiants

  • HAL Id : medihal-01723131 , version 1

Citer

Haiying Du, Yohan Dudognon, Jean Rodriguez, Thierry Constantieux, Xavier Bugaut. Weinreb β-Ketoamides in Enantioselective Organocatalysis: A Balance between Reactivity and Selectivity. Illustration. France. 2017. ⟨medihal-01723131⟩
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