Image (Photographie) Année : 2008

Sterically Hindered Benzophenones via Rhodium-Catalyzed Oxidative Arylation of Aldehydes

Résumé

Efficient cross-coupling, allowing a straightforward access to congested benzophenones, between aromatic aldehydes and potassium aryltrifluoroborates, is described in the presence of a rhodium/tri-tert-butylphosphane catalyst system and acetone as cosolvent. The use of the stable phosphonium salts of tri-tert-butylphosphane prevented the use of highly oxidizable tri-tert-butylphosphane and allowed a careful control of the stoichiometry with the rhodium.

HAL

Décrit hal-01722832 Article Olivier Chuzel, Alexander Roesch, Jean-Pierre Genêt, Sylvain Darses. Sterically Hindered Benzophenones via Rhodium-Catalyzed Oxidative Arylation of Aldehydes. Journal of Organic Chemistry, 2008, 73 (19), pp.7800 - 7802. ⟨10.1021/jo801460w⟩. ⟨hal-01722832⟩

Dates et versions

medihal-01722965 , version 1 (05-03-2018)

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  • HAL Id : medihal-01722965 , version 1

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Olivier Chuzel, Alexander Roesch, Jean-Pierre Genêt, Sylvain Darses. Sterically Hindered Benzophenones via Rhodium-Catalyzed Oxidative Arylation of Aldehydes. Photography. France. 2008. ⟨medihal-01722965⟩
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